The requirement for compound ophthalmic drugs
The compounding of ophthalmology drugs has many reasons. It is simply the matter of consolidation, dosage and specifically format that is eye drops and ointments. Eye drops are the most common drug delivery method then ointments, but both can be easily available and adequately compounded.
Many kinds of ophthalmic drugs can only be acquired through compounding. Patients have a different toleration capacity and not every patient is able to tolerate preservatives. So characterization of preservative free drugs for the ophthalmic drug market is vital. Some of the combined drugs that are not obtained commercially are combined anesthetic and dilating agents mixed allergy solutions and combined antimicrobial drops. In the case of treatment, the demand for the drug is high but the availability is far outpaced. Specific requirement of patients, specific consideration regarding ocular agents highlights the rising demand for majorly compounded ophthalmic medications for eye diseases treatments. The commonly used ophthalmic medications are commercially not available or widespread use would not have the approval of FDA. Many reasons go along for a drug not to be available specifically in the treatment of ocular disorders. Reasons for the products that cannot be obtained on a commercial level are limited shelf life and stability. This case is repeatedly seen in antibiotic ophthalmic drugs and also in combined antibiotic ophthalmic drug, both topical and injectable varieties that are combined from preparations that are available commercially that too for a limited period of time. They must not be kept more than 14 days in temperature maintained conditions. Few of the ophthalmic medications are fairly typical for use in the case; in a pharmaceutical sense are “special needs”. Some patients require brilliant blue G dye, which is commercially not available. Other patients need compounding because their regimen is specific. For example, certain ophthalmic patients such as those with extreme dry eye issue must have autologous serum eye drops that make use of their own serum.
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Most Common Ophthalmic drugs
Patients with extremely dry eyes may need ointments or eye drops to reduce the inflammation around the surface of the eyes. Autologous serum eye drops treatment, is to solve the problem using the serum of the patient itself. Delay in bacterial corneal ulcer treatment or insufficient treatment can have serious effects in a short time that include corneal perforation and scarring, even blindness. A compounded fortified topical antibiotic is the preferred course of treatment. Fungal keratitis is particularly dangerous because it develops rapidly and can cause blindness if untreated. It is treated with antifungal agents, usually in eye drops; these treatments are effective when customized. There are two kinds of antifungal agents used in ophthalmic medications: polyenes and triazoles.
Ophthalmologists need reliable, skilled compounding providers with access to the best supplies and information. There will always be a need for compounded ophthalmic medications for a varied application, so this exclusive area will be robust and a driver to the ophthalmology drugs and devices market.
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Author: Komal Surana
Sr. Content Writer and Editor, Inkwood Research